The purpose of this study is to determine the effects of the pandemic on marital relationships and sexual life. This descriptive cross-sectional study was carried out between 20 November 2020 and 31 January 2021 nationwide in Turkey by using an online survey form. A “Participant Information Form” developed by the researchers by reviewing the literature was used to collect data.  The study included 417 women with a mean age of 32.37±6.41 years and an average marriage duration of 7.84±7.07 years. It was determined that the sexual intercourse frequency of the women decreased in the COVID-19 pandemic period in comparison to before the pandemic (P<0,001). Women who were separated from their spouses due to the risk of transmission, whose marital relationship and sexual life were negatively affected by COVID-19, or whose spouses had sexual problems, showed a statistically significant decrease in the frequency of sexual intercourse (p < 0.05).  Among women whose marriage was negatively affected by COVID-19, 47.3% reported changes in the frequency of sexual intercourse, 36.3% in vaginal lubrication, 31.9% in orgasm frequency, 44% in sexual satisfaction, 18.7% in pain or discomfort during intercourse, and 14.3% experienced differences in the presence of sexual problems in their spouse (p < 0.05). A significant relationship was found between the effect of COVID-19 on marriage and sexual desire, with 53.8% of women whose marriage was negatively affected by COVID-19 reporting changes in sexual desire (p<0,001). It was concluded that, in the COVID-19 pandemic period, the sexual intercourse frequency of the women decreased, their relationships with their spouses and sexual functions were negatively affected, and their statuses of COVID-19 affecting their marriage were related to their sexual functions.